The kidney plays a crucial role in metabolic elimination and is a target organ for drug action. The renal tubules are responsible for reabsorbing glucose and water, as well as excreting certain drugs through secretion. As such, the kidney is of significant importance in studying drug-induced renal injury and drug interactions.
The human primary proximal renal tubule model independently developed by Daxiang can effectively retain the differentiation of renal tubular epithelial cells and the maintenance of stem cells. It is an ideal in vitro model for renal function research, drug absorption and drug nephrotoxicity assessment.