Wechat scan consulting
Wechat scan consulting
28
A new addition to the Oukoryn™ portfolio, PCS-Smart offers precise, flexible perfusion control for organoid, cell culture, and organ-on-a-chip research.
Daxiang Biotech has introduced Oukoryn™ PCS-Smart, a high-throughput intelligent perfusion system designed to support advanced dynamic cell culture and microfluidic research.
Combining independent multi-channel control, customizable perfusion settings, and intuitive software, PCS-Smart enables researchers to establish controlled dynamic culture environments across a range of experimental models. The system is designed to accommodate diverse research workflows, from organoid cultivation and tissue engineering to drug screening and barrier function studies.
As organoid and microphysiological models become increasingly sophisticated, maintaining stable and reproducible culture conditions remains an important consideration in experimental design.
PCS-Smart addresses this need through a compact, modular platform that supports up to 10 independently controlled perfusion channels. Researchers can adjust flow rates and configure continuous or intermittent perfusion to accommodate different experimental requirements.
The system also features software-based parameter control and real-time monitoring, allowing researchers to manage perfusion conditions and experimental protocols through a centralized interface.
With its flexible configuration and compatibility with various microfluidic chips and external perfusion modules, PCS-Smart can be integrated into a range of dynamic culture workflows.
PCS-Smart is designed to support a broad range of in vitro research applications, including:
Organoid and Organ-on-a-Chip Culture: Providing controlled perfusion conditions for dynamic cultivation of organoid and microphysiological models.
High-Throughput Drug Screening: Supporting parallel experimental workflows for drug efficacy evaluation and toxicity assessment.
Stem Cell and Regenerative Medicine Research: Enabling dynamic culture environments for stem cell studies and tissue engineering applications.
Organoid Biobanking and Standardization: Supporting more consistent and scalable culture workflows through programmable perfusion control.
These capabilities make PCS-Smart a versatile addition to laboratories seeking greater flexibility in dynamic cell culture and experimental workflow design.
The potential value of dynamic perfusion is illustrated by application data generated using Caco-2 intestinal barrier models.
Compared with static culture conditions, dynamic perfusion culture was associated with enhanced expression of the tight junction protein ZO-1 and the intestinal epithelial marker Villin, alongside higher transepithelial electrical resistance (TEER) measurements.
These findings suggest that controlled perfusion can help support the structural and functional characteristics of intestinal barrier models under the conditions evaluated.
Beyond intestinal barrier research, PCS-Smart has also been demonstrated in the dynamic culture of various organoid and cell models, including lung cancer and intestinal cancer models, taste bud models, and cancer-associated fibroblasts (CAFs).
Together, these applications illustrate the system's flexibility across different biological models and experimental requirements.
The introduction of PCS-Smart further expands Daxiang Biotech's Oukoryn™ portfolio of instruments and supporting technologies for organoid and organ-on-a-chip research.
By bringing together programmable perfusion control, modular system design, and compatibility with diverse culture platforms, PCS-Smart is designed to help researchers develop more adaptable and controlled experimental workflows.
As Daxiang Biotech continues to advance its organoid-on-a-chip technology portfolio, the company remains focused on developing integrated tools and solutions that support human-relevant in vitro research and drug discovery.
Learn More
For more information about Oukoryn™ PCS-Smart and its research applications, visit www.daxiangbio.com or contact service@daxiangbio.com.
