Designed to support controlled fluid movement and flexible experimental workflows in organoid-on-chip and advanced in vitro research.

Daxiang Biotech has introduced PCS-Light, a high-throughput gravity-driven precision rocker designed to support dynamic cell culture across organoid-on-chip, microfluidic, and other advanced in vitro research applications.

Featuring precise motion control, multiple operating modes, and 12- or 24-position configurations, PCS-Light enables researchers to introduce controlled, gravity-driven fluid movement into compatible culture systems without the need for external pumps.

Bringing Controlled Fluid Movement to Advanced In Vitro Models

Dynamic culture conditions play an important role in the development and study of advanced in vitro models. While conventional static culture remains widely used, introducing controlled fluid movement can help researchers investigate how cells and tissues respond to mechanical and environmental conditions.

For organoid-on-chip and microphysiological system (MPS) research, fluid movement can be particularly relevant to studies involving barrier function, cell–microenvironment interactions, and tissue responses under dynamic conditions.

PCS-Light uses programmable rocking motion to generate gravity-driven fluid movement within compatible culture platforms. Its adjustable operating parameters allow researchers to tailor culture conditions to different experimental requirements.

Designed for Precision, Flexibility, and Throughput

PCS-Light combines several features to support dynamic culture workflows:

• High-throughput configurations: Available in 12-position and 24-position models to accommodate parallel experiments.

• Multiple operating modes: Supports different motion patterns for a range of experimental requirements.

• Precise motion control: Adjustable rocking angle and speed allow researchers to configure operating conditions.

• Pump-free operation: Gravity-driven fluid movement reduces the need for external pumping systems and associated tubing.

• Flexible chip compatibility: Designed to accommodate different compatible chip formats and experimental setups.

These capabilities provide laboratories with a flexible approach to incorporating dynamic fluid movement into cell culture experiments.

Applications in Organoid-on-Chip and Cell Culture Research

PCS-Light is designed for applications involving dynamic culture and controlled fluid movement, including:

• Organ-on-Chip and Microfluidic Models

  Supporting gravity-driven fluid movement in compatible microfluidic systems for studies of cellular behavior and fluid–cell interactions.
  

• Organoid Culture

  Providing controlled rocking conditions for compatible three-dimensional culture systems and organoid research workflows.
  

• Barrier Models and Functional Evaluation

  Supporting experimental studies of epithelial and endothelial barrier models, including investigations of barrier integrity and cellular responses under dynamic culture conditions.

Supporting Integrated Organoid-on-Chip Workflows

As organoid-on-chip and MPS technologies continue to develop, integrating appropriate instrumentation into experimental workflows is an important consideration for researchers seeking practical and reproducible approaches to advanced cell culture.

PCS-Light complements Daxiang Biotech's portfolio of IBAC® biomimetic array chips, organoid-on-chip models, and supporting laboratory instrumentation, providing an additional option for incorporating controlled dynamic culture conditions into compatible research platforms.

The instrument is available in two configurations: PCS-L12 (12 positions) and PCS-L24 (24 positions).

For technical specifications, compatibility information, or product inquiries, please contact the Daxiang Biotech team.